What’s the cost of a flight from Guayaquil to Santo Domingo La Isabela?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Guayaquil and Santo Domingo.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

Are there multiple airports in Guayaquil and Santo Domingo?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Guayaquil: Only Guayaquil operates in this city.
• Airports in Santo Domingo: Santo Domingo - La Isabela is the only airport currently running.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Explore flights from Guayaquil to Santo Domingo La Isabela your way

On Jetcost, you can filter by round-trip or one-way, time of day, airline, number of stops, and even by specific travel agency.

Other popular destinations

Also interested in Dominican Republic? Check out: Puerto Plata, Punta Cana, Samaná, Santiago, Santo Domingo.

If you’re flexible with dates, try checking the days before and after to see if prices vary. Some routes are offered by multiple agencies — comparing fares can really pay off.