Find out what a flight from Panama City to Santo Domingo La Isabela might cost

Prices vary based on date, airline, and availability. Compare several options if you're flying between Panama City and Santo Domingo.

Select your dates to check current offers.

Try shifting your departure forward or backward by a day to find better options. If you’re looking for a good deal, consider flying outside peak hours as well.

What are the airport options between Panama City and Santo Domingo?

If both departure and destination cities offer multiple airports, comparing them can help you save time and money.

• Airports in Panama City: Panama City has 2 airports - Pacífico International Airport, Paitilla.
• Airports in Santo Domingo: Santo Domingo has one airport operating, Santo Domingo - La Isabela.

Some airports have different terminals for low-cost and traditional airlines — knowing in advance can save time. You can filter results to see only the airports that suit you.

Find flights from Panama City to Santo Domingo La Isabela that suit your schedule

Use Jetcost to sort and filter results based on your preferred flight time, number of stops, price range, or airline. View deals from the best airlines and travel agencies.

Other popular destinations

Interested in Dominican Republic? These cities are also in demand: La Romana, Puerto Plata, Punta Cana, Santiago, Santo Domingo.

Connecting flights can be cheaper but often mean longer layovers. You can easily select either direct or connecting flights with a single click using the filters.